Blar i forfatter "Göschl, Lorenz"

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    • Detection of DHCMT long-term metabolite glucuronides with LC-MSMS as an alternative approach to conventional GC-MSMS analysis 

      Göschl, Lorenz; Gmeiner, Günter; Gärtner, Peter; Steinacher, Michael; Forsdahl, Guro (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-02-17)
      Dehydrochloromethyltestosterone (DHCMT) is one of the most detected illicit used anabolic–androgenic steroids in professional sports. Therefore, a fast and accurate analysis of this substance is of great importance for a constructive fight against doping abuse. The conventional method for the analysis of this drug, GC-MSMS, is very sensitive and selective but also very time- and resource-consuming. ...

    • Development and validation of a simple online-SPE method coupled to high-resolution mass spectrometry for the analysis of stanozolol-N-glucuronides in urine samples 

      Göschl, Lorenz; Gmeiner, Günter; Enev, Valentin S; Kratena, Nicolas; Gärtner, Peter; Forsdahl, Guro (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-04-17)
      Stanozolol is still the most commonly used illicit anabolic‐androgenic steroid (AAS) in professional sports. Therefore, accurate and fast analysis and long detection windows are of great interest in the field of antidoping analysis. In this work, a very simple, fast, and highly sensitive online solid‐phase extraction method coupled with liquid chromatography–high‐resolution tandem mass spectrometry ...

    • Discovery and detection of phase-II metabolites of exogenous steroids in anti-doping analysis 

      Göschl, Lorenz (Doctoral thesis; Doktorgradsavhandling, 2022-04-29)
      Anti-doping measures are an essential part of professional sports around the world. Anabolic androgenic steroids have been among the most widely used illicit substance classes since the early days of the fight against doping. The conventional method for analysing these substances is gas chromatography combined with mass spectrometry (GC-MS). This approach is sensitive and selective but also very ...

    • Stanozolol-N-glucuronide metabolites in human urine samples as suitable targets in terms of routine anti-doping analysis 

      Göschl, Lorenz; Gmeiner, Günter; Gärtner, Peter; Stadler, Georg; Enev, Valentin; Thevis, Mario; Schänzer, Wilhelm; Guddat, Sven; Forsdahl, Guro (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-05)
      The exogenous anabolic-androgenic steroid (AAS) stanozolol stays one of the most detected substances in professional sports. Its detection is a fundamental part of doping analysis, and the analysis of this steroid has been intensively investigated for a long time. This contribution to the detection of stanozolol doping describes for the first time the unambiguous proof for the existence of ...